Genetic Testing for Embryos in Noida Advanced Preimplantation Genetic Testing (PGT) for selected IVF patients and couples with genetic or chromosomal concerns
If you have a known inherited genetic condition, recurrent pregnancy loss, a chromosomal rearrangement, or have been advised to consider embryo genetic testing during IVF, genetic testing for embryos in Noida may be discussed as part of your fertility treatment.
What is Genetic Testing for Embryos?
Genetic testing in IVF commonly refers to Preimplantation Genetic Testing (PGT). PGT involves testing cells from embryos created through IVF to obtain information about certain chromosome or genetic abnormalities before an embryo is selected for transfer.
Depending on the indication, different forms of PGT may be considered: PGT-A, PGT-M, and PGT-SR. These tests answer different genetic questions and should not be considered interchangeable.
At Divine IVF, Sector 76, Noida, Dr. Mandavi Rai provides personalised fertility evaluation and IVF treatment planning for couples who may require Preimplantation Genetic Testing (PGT). Depending on your medical and family history, genetic counselling and specific genetic testing may be recommended before deciding whether PGT is appropriate.
How it works
Step 1 – Fertility and Medical Consultation
Your fertility specialist reviews reproductive history, previous pregnancies, miscarriages, previous IVF cycles, family history, known genetic disorders, and previous genetic reports.
Step 2 – Genetic Evaluation if Required
Depending on the indication, you may be advised to undergo carrier screening, karyotype, disease-specific genetic testing, genetic counselling, or additional laboratory investigations.
Step 3 – IVF Planning
Because embryo genetic testing requires embryos, PGT is generally performed as part of IVF. The female partner undergoes ovarian stimulation to develop multiple follicles.
Step 4 – Egg Retrieval
Once follicles are ready, eggs are retrieved from the ovaries and transferred to the embryology laboratory.
Step 5 – Fertilisation
Eggs are fertilised using IVF or ICSI according to the clinical and laboratory plan.
Step 6 – Embryo Culture
Fertilised eggs are cultured in the laboratory. Suitable embryos may develop to the blastocyst stage over several days.
Step 7 – Embryo Biopsy
A small number of cells may be removed from the outer portion of a suitable blastocyst. The biopsy sample is then prepared for genetic testing.
Step 8 – Embryo Freezing
Embryos are commonly frozen after biopsy while genetic results are processed.
Step 9 – Genetic Laboratory Analysis
The biopsied cells are analysed according to the type of PGT being performed: PGT-A, PGT-M, or PGT-SR.
Step 10 – Results and Counselling
Results are reviewed with the couple. The fertility and genetics teams explain which embryos may be considered for transfer and any limitations of the findings.
Step 11 – Frozen Embryo Transfer
If a suitable embryo is available, a frozen embryo transfer cycle may be planned. The uterine lining is prepared and the selected embryo is transferred.
Benefits
- Provides Genetic Information Before Embryo Transfer — PGT can provide information about selected genetic or chromosomal abnormalities before an embryo is transferred
- May Help Couples With Known Inherited Conditions — PGT-M can help couples at risk of transmitting certain known inherited diseases
- Helps With Structural Chromosome Rearrangements — PGT-SR may help couples where one partner carries an appropriate structural chromosome rearrangement
- Supports Informed Embryo Selection — Testing results may provide additional information when choosing embryos for transfer
- Enables Personalised Fertility Planning — PGT can be incorporated into IVF only when there is an appropriate clinical or genetic indication
- May improve implantation rates by selecting chromosomally normal embryos
Things to know
- Cannot detect every genetic disorder
- Cannot guarantee pregnancy
- Cannot guarantee a healthy baby
- May produce inconclusive results
- May identify mosaic findings
- Requires an IVF cycle
- May increase overall treatment cost
- May result in no embryos being suitable for transfer
- Embryo biopsy carries a small risk of affecting embryo development
Getting ready
Some couples may require genetic testing even before starting an IVF cycle. Testing can include carrier screening, karyotyping, disease-specific genetic testing, assessment based on family history, and genetic counselling.
If you're considering testing for a specific inherited condition (PGT-M), this is best discussed well before your cycle begins. It may involve additional preparatory genetic testing of both partners to design the correct genetic screen for the embryos.
Genetic counselling is an essential part of the process. A genetic counsellor can help explain why testing is being considered, which test is appropriate, what the possible results mean, what cannot be detected, the chance of inconclusive results, reproductive options, and whether relatives may need testing.
What to expect
Because samples are sent to a specialised genetics lab, results generally take 7-14 days to come back — longer than standard embryo assessment. This is factored into your transfer timeline, and involves vitrifying (freezing) embryos while awaiting results. The actual biopsy procedure is performed by an experienced embryologist under a high-powered microscope using micromanipulation tools. PGT does not guarantee pregnancy or the birth of a baby without health problems.
Genetic Testing for Embryos in Noida
Advanced Preimplantation Genetic Testing (PGT) for selected IVF patients and couples with genetic or chromosomal concerns.
📍 Sector 76, Noida, Uttar Pradesh
📞 Call: +91 7678451808
What Is Genetic Testing in IVF?
Genetic testing in IVF commonly refers to Preimplantation Genetic Testing (PGT).
PGT involves testing cells from embryos created through IVF to obtain information about certain chromosome or genetic abnormalities before an embryo is selected for transfer.
Depending on the indication, different forms of PGT may be considered:
- PGT-A — Preimplantation Genetic Testing for Aneuploidy
- PGT-M — Preimplantation Genetic Testing for Monogenic Disorders
- PGT-SR — Preimplantation Genetic Testing for Structural Rearrangements
These tests answer different genetic questions and should not be considered interchangeable.
Types of Genetic Testing for Embryos
PGT-A – Preimplantation Genetic Testing for Aneuploidy
PGT-A evaluates the number of chromosomes present in sampled embryo cells. A typical human cell has 46 chromosomes. An embryo with the expected chromosome number is commonly described as euploid, while an embryo with missing or extra chromosomes may be described as aneuploid.
PGT-A may be discussed in selected IVF cases, but it should not automatically be used for every IVF patient.
Who May Discuss PGT-A?
- Advanced maternal age
- Recurrent pregnancy loss
- Repeated unsuccessful IVF treatment
- Certain previous chromosomal findings
- Other situations identified by the fertility specialist
PGT-M – Preimplantation Genetic Testing for Monogenic Disorders
PGT-M is used when there is a known risk of passing a specific single-gene condition to a child. Examples may include certain inherited disorders where the causative genetic variant has already been identified.
PGT-M is generally performed as part of IVF even when a couple does not otherwise have infertility.
Who May Consider PGT-M?
- One partner has a known inherited genetic condition
- Both partners carry variants for the same recessive genetic condition
- There is a serious inherited condition in the family
- A previous child has been affected by a known genetic disorder
- Genetic testing has identified a specific disease-causing variant
- A genetic specialist recommends embryo testing
Because PGT-M is condition-specific, genetic counselling and test development may be required before the IVF cycle.
PGT-SR – Preimplantation Genetic Testing for Structural Rearrangements
PGT-SR is used in selected couples where one partner carries a known structural chromosome rearrangement. Examples may include balanced translocations, certain inversions, and other clinically relevant chromosome rearrangements.
These abnormalities may increase the likelihood of embryos having unbalanced chromosome material. PGT-SR can help evaluate embryos for relevant chromosome imbalance before transfer.
PGT-A vs PGT-M vs PGT-SR
PGT-A
Evaluates chromosome number abnormalities.
PGT-M
Tests embryos for a specific known single-gene disorder.
PGT-SR
Evaluates embryos when a parent carries a known structural chromosome rearrangement.
The correct test depends on your genetic history and clinical indication.
What Is Genetic Carrier Screening?
Carrier screening can help identify whether an individual carries certain inherited genetic conditions. A carrier may be healthy but could pass a disease-related genetic variant to their child.
When both partners carry variants affecting the same recessive condition, genetic counselling can help explain reproductive risks and available options.
Not every couple requires the same carrier-screening panel.
Why Is Genetic Counselling Important?
Genetic counselling is an important part of reproductive genetic testing. A genetic counsellor or appropriately trained specialist can help explain:
Genetic counselling is particularly important when PGT-M is being considered.
Does Genetic Testing Guarantee a Healthy Baby?
No.
PGT can provide information about specific chromosome or genetic abnormalities, but it cannot test for every possible medical, developmental or genetic condition.
It also does not guarantee:
Prenatal screening or diagnostic testing may still be discussed during pregnancy.
Important Considerations About PGT
How Accurate Is PGT?
Modern genetic testing can provide valuable information, but no genetic test is perfect. Possible limitations include no-result or inconclusive findings, mosaic results, sampling limitations, laboratory limitations, rare diagnostic errors, embryos unsuitable for biopsy, and no suitable embryo being available after testing. These possibilities should be discussed before treatment.
What Is a Mosaic Embryo?
A mosaic result generally means that the sampled cells show a mixture of cells with different chromosome findings. Interpretation can be complex. Decisions about whether a mosaic embryo should be considered for transfer require careful discussion with the fertility team and, where appropriate, a genetics specialist.
Does Embryo Biopsy Damage the Embryo?
Embryo biopsy is a specialised laboratory procedure. Most embryos continue to develop after an appropriately performed biopsy, but the procedure is not completely risk-free. There is a small possibility that an embryo may be affected or may not survive later processes such as freezing and thawing.
Is PGT-A Recommended for Every IVF Patient?
No.
PGT-A should not automatically be added to every IVF cycle. Whether it may be useful depends on factors such as:
The potential advantages, costs and limitations should be discussed before deciding.
Benefits of Genetic Testing in IVF
- ✓ Provides Genetic Information Before Embryo Transfer PGT can provide information about selected genetic or chromosomal abnormalities before an embryo is transferred.
- ✓ May Help Couples With Known Inherited Conditions PGT-M can help couples at risk of transmitting certain known inherited diseases.
- ✓ Helps With Structural Chromosome Rearrangements PGT-SR may help couples where one partner carries an appropriate structural chromosome rearrangement.
- ✓ Supports Informed Embryo Selection Testing results may provide additional information when choosing embryos for transfer.
- ✓ Enables Personalised Fertility Planning PGT can be incorporated into IVF only when there is an appropriate clinical or genetic indication.
Limitations of Genetic Testing in IVF
Patients should understand that PGT:
Proper counselling before testing is important.
Genetic Testing Cost in Noida
The cost of genetic testing in IVF in Noida varies depending on the type of testing and the overall fertility treatment plan. Costs may include:
PGT-M may also involve condition-specific testing preparation. An accurate cost estimate can therefore only be given after the required test has been identified.
Why Choose Divine IVF for Genetic Testing
- ✓Personalised Fertility Assessment — Genetic testing is considered according to each couple`s reproductive history and clinical findings rather than being routinely recommended to everyone.
- ✓IVF Treatment Planning — Embryo genetic testing can be incorporated into an IVF treatment plan when clinically appropriate.
- ✓Evaluation of Both Partners — Family history and fertility factors involving both partners are considered.
- ✓Advanced Fertility Options — Depending on the fertility diagnosis, treatments may include IVF, ICSI and embryo genetic testing where appropriate.
- ✓Doctor-Led Fertility Care — Treatment planning is provided under the guidance of Dr. Mandavi Rai, Gynecologist & IVF Specialist in Noida.
- ✓Convenient Noida Location — Divine IVF is located in Sector 76, Noida, for couples seeking fertility evaluation and advanced reproductive treatment.
Book a Genetic Testing Consultation in Noida
If you have a family history of a genetic disorder, recurrent pregnancy loss, a known chromosome rearrangement, or have been advised to consider embryo genetic testing, a detailed consultation can help determine the appropriate next step. At Divine IVF, Sector 76, Noida, Dr. Mandavi Rai provides personalised IVF treatment planning based on your fertility and medical history.
Divine IVF · Sector 76, Noida, Uttar Pradesh
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Common questions
Genetic testing in IVF generally refers to Preimplantation Genetic Testing, where cells from embryos are analysed for selected genetic or chromosomal abnormalities before embryo transfer.
PGT stands for Preimplantation Genetic Testing.
PGT-A evaluates chromosome number, while PGT-M is designed to test for a specific known single-gene disorder.
PGT-SR is used in selected cases where one parent carries a structural chromosome rearrangement.
No. PGT-A is not routinely necessary for every patient. Its potential benefit should be assessed individually.
No. PGT cannot detect every genetic or medical condition.
PGT may provide useful information in selected cases, but it cannot guarantee that miscarriage will not occur.
No. Implantation and pregnancy depend on many factors beyond the genetic test result.
Embryos need to be created in the laboratory before preimplantation genetic testing can be performed, so PGT is carried out as part of IVF.
Embryos are commonly frozen while the biopsy sample undergoes laboratory testing. A suitable embryo may later be transferred in a frozen embryo transfer cycle.
PGT-M may be used for selected known inherited single-gene disorders when an appropriate genetic test can be developed.
Cost depends on the type of PGT, number of samples, IVF treatment, embryo biopsy, genetic laboratory charges and other fertility procedures.
You can consult Dr. Mandavi Rai at Divine IVF, Sector 76, Noida for fertility evaluation and personalised discussion regarding IVF and embryo genetic testing.
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